The Life Savers

Together for a Healthier Tomorrow

PSA (Prostate-Specific Antigen) Test

A blood test that measures prostate-specific antigen (PSA), a protein made by the prostate gland.

PSA (Prostate-Specific Antigen) Test

A blood test that measures prostate-specific antigen (PSA), a protein made by the prostate gland.

Also known as

What it measures

Why a doctor may order it

It can be used to screen for prostate cancer, and it may also be ordered if you have symptoms of a prostate condition. Screening with a PSA test is a personal choice with possible harms: it cannot tell cancer from non-cancerous conditions, and many prostate cancers grow so slowly they never cause problems.

What it helps evaluate

A higher PSA can be caused by prostate cancer or by conditions that are not cancer, such as an infection or an enlarged prostate, and a normal PSA does not completely rule out cancer. A high result usually leads to more tests, not a diagnosis.

Preparation

Avoid sex and masturbation for 24 hours before the test, because releasing semen can raise PSA and make the result less accurate. Certain medicines can also affect the result — tell your provider about everything you take.

Fasting

No fasting is needed.

Important considerations

Discuss results with your doctor

Talk to a doctor about whether PSA screening is right for you, and about any urinary or prostate symptoms.

Explore The Life Savers

Official and Reference Resources